PROOF in the Publishing: Slicing the Data on Pridopidine
Pridopidine has been under investigation as a treatment for Huntington’s disease (HD) since the early 2000s. The most recent Phase 3 trial testing to see if pridopidine might improve signs and symptoms of HD, a study called PROOF-HD, did not meet its key goals. Furthermore, this summer we learned that the European Medicines Agency (EMA) […]
2025 HDBuzz Prize: ACTing on HD: Exploring Acceptance and Commitment Therapy to Improve Mental Health in People with Huntington’s Disease and Their Caregiver
A group of researchers at the University of Pennsylvania, USA, has recently carried out an investigation to explore whether using a type of talking therapy, called Acceptance and Commitment Therapy (ACT), can help improve the mental wellbeing of people affected by Huntington’s disease (HD). The study, published in the Journal of Huntington’s Disease, combines a short review […]
2025 HDBuzz Prize: Calm Before the Storm: Early Clues of Huntington’s Disease Found in Brainwaves
We know that HD affects how we move, think, and feel but these symptoms don’t appear overnight. Tiny hidden changes in the brain can begin years before a diagnosis. One way that scientists can detect these early shifts is by measuring brainwaves. This is a painless, non-invasive way to see how the brain is working […]
Falling Into Hope: HDBuzz Fundraising Campaign 2025
This Fall, HDBuzz is proud to launch our “Falling Into Hope” fundraising campaign. Our goal is simple but ambitious: raise $30,000 in the next 8 weeks, by October 28. 2025 will be a landmark year in HD research. We’re closer than ever to disease-modifying therapies, and clear, unbiased reporting has never been more essential. HDBuzz […]
August 2025: This Month In Huntington’s Disease Research
This month’s Huntington’s disease (HD) research roundup spans work from the dinner table to DNA repair. Scientists explored whether eating on a schedule could help clear toxic proteins, uncovered early signs of muscle loss in HD, and examined how childhood experiences shape adult mental health. Other teams investigated the gut–brain connection, identified new protein biomarkers, […]
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