May 2025: This Month in Huntington’s Disease Research
May was a month packed with exciting research, and we’ve got the highlights ready for you – no lab coat required! From genetic mysteries to vision changes and dental awareness, researchers uncovered some fascinating stuff about Huntington’s disease (HD) this month. And we heard an exciting clinical trial update from PTC Therapeutics. Buckle up for […]
Mind Your Mouth: Huntington’s Disease and Oral Health
Seeking dental care and adhering to recommended routines is tough for lots of folks, even under the best of circumstances. Throw Huntington’s disease (HD) into the mix, and oral health can get even tougher. A recently published review paper in the journal Special Care in Dentistry covers some of the challenges faced by HD families […]
DNA Repair in Huntington’s Disease: Not Up to Par?
Scientists are working to understand some of the earliest changes to DNA repair caused by Huntington’s disease (HD) – insights that could help uncover new therapeutics and new ways to target somatic expansion, a key driver of disease progression. A molecule that helps fix DNA damage – called PAR – is lower than expected in […]
Unlocking the Mind’s Eye: How Huntington’s Disease Changes How We See and Process the World
Imagine waking up one day and realizing that the world around you no longer looks the same. Faces are harder to recognize, navigating familiar streets feels confusing, and reading a book becomes a frustrating puzzle. This unsettling scenario is a reality for many people affected by Huntington’s disease (HD). Dr Juan Carlos Gómez-Esteban and his […]
Red Light, Green Light: How Huntington’s Disease Influences Genetic Traffic Lights
For Huntington’s disease (HD), a lot of attention goes to the genetic change that causes HD, but new research is shining a light on something else – our epigenome. The word literally means, “above” the “genome”, or above the genetic code. It’s a layer of chemical marks that are added to genes to regulate their […]
Navigating the Genetic River: How Tiny Variants Could Shift the Course of Huntington’s Disease
Imagine the gene that causes Huntington’s disease (HD) as a vast river. At its source is the CAG repeat – a genetic letter code that dictates how the river will flow. As the river moves downstream, it transitions into the letter code CCG, forming a continuous current. But what if, hidden beneath the surface, tiny […]
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