The Number on the Scale: What the TFC Score Measures, and Why It Matters Right Now

⏱️ 10 min read | The Total Functional Capacity score has been used in Huntington’s disease research for decades. Here’s what it measures, what it misses, & why it’s at the center of an anticipated clinical trial. Read more
Fund the Buzz: The $8,000 Reason HDBuzz Can Tell You the Truth

⏱️ 6 min read | HDBuzz is launching Fund the Buzz, our spring fundraising campaign! We’re independent, pharma funding-free, and run by scientists who know HD. Help us keep the lights on (and stay lawsuit-free). Read more
Cutting to the chase with CRISPR

⏱️ 6 min read | A new study uses “self-switching” genetic scissors to target the root cause of Huntington’s disease in mice – even after symptoms begin. Read more
Artificial Intelligence enters the HD space as a diagnostic tool

⏱️9 min read | From predicting symptom onset to tracking movement changes via smartwatch, artificial intelligence tools are being used in research. Here’s where we are, and why Huntington’s disease is a strong candidate for these approaches. Read more
Blocking a toxic fragment: new mouse study highlights the importance of HTT1a in Huntington’s disease

⏱️ 9 min read |New research in a HD mouse model points to a key culprit: a small fragment called HTT1a. Lowering HTT1a levels successfully delayed disease signs in mice that model HD, perhaps shaping the next generation of HTT-lowering therapies. Read more